Candesartan CAS: 139481-59-7 Manufacturer Supplier

Candesartan est angiotensin receptor I (AT1) antagonista, IC50s=1.12 et 2.86 nM cortex adrenalis et leporis aortae bubulae respective. Selective vetat angiotensin II contractionem inductam contractionem pituitae aortae nullo effectu contractionis ab aliis agentibus ut norepinephrinam inducta. , KCl, serotonin, PGF2αor endothelin.

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Application et effectus

Candesartan est AT1 selectivum (angiotensin II receptor 1) adversario.Oppugnatio receptorum angiotensin inhibet vasoconstrictionem et aldosteronis productionem, ad diminutionem in aqua et sodium concentratio in plasmate sanguinis.Effectus antihypertensivos in animalibus exemplaribus exhibet.Usus est in curatione defectus cordis congestivi, ut antihypertensive.Candesartan cellam viability vel multiplicationem non afficit, sed expressionem VEGF et interleukin-8 in medio exculto cellularum KU-19-19 auget.Candesartan (0.1 nM) responsionem maximam contractilem ad angiostensin II per circiter 50 minuere potuit.

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Compositio	C24H20N6O3
Assay	99%
Aspectus	Pulvis albus
CAS Non.	139481-59-7
stipare	1KG 25KG
Fasciae vita	Annis II
Repono	Condite in frigus et siccum area
Certification	ISO.